CCH Pipeline

Indication
Preclinical
Phase 1
Phase 2
Phase 3
Marketed
XIAFLEX® COMMERCIAL INDICATIONS
Dupuytren’s Contracture
Peyronie’s Disease
UNDER FDA REVIEW
Cellulite
XIAFLEX® DEVELOPMENT INDICATIONS
Adhesive Capsulitis
Plantar Fibromatosis

Plantar fibromatosis:
Plantar fibromatosis involves pain and disability caused by the thickening of the feet's deep connective tissue and patients often have Dupuytren’s disease, Peyronie’s disease and adhesive capsulitis. Current treatments include orthotics and anti-inflammatory drugs in the early stages of the disease, steroid injections and surgery in advanced cases.

Adhesive capsulitis:
Adhesive capsulitis involves inflammation and thickening of shoulder capsule due to collagen, limiting the range of motion of the shoulder. Common available treatment options are often painful and can require anesthesia and this condition can last from about one year to over three.